What Conditions Disqualify Immigration?
September 20, 2025
Immigration to the United States is a life-changing process, but it comes with strict requirements. One of the most important steps involves the immigration medical exam, which ensures that applicants meet the health standards set by U.S. Citizenship and Immigration Services (USCIS). During this process, some conditions may prevent an applicant from being approved for immigration benefits.
At Immigration Medical Exam Clinic, we often get asked: What conditions disqualify immigration? This guide explains the main categories of health-related grounds of inadmissibility, what tests are involved, and what applicants should expect when completing their medical exam.
Understanding Immigration Medical Inadmissibility
Before looking at the specific conditions, it’s important to understand what “inadmissibility” means.
- Inadmissibility: Certain medical, legal, or security-related factors can prevent someone from entering or staying in the United States.
- Medical Inadmissibility: This focuses on health conditions that could endanger public safety, create high healthcare costs, or affect an applicant’s ability to meet immigration requirements.
The immigration medical exam is designed to identify these conditions. A designated civil surgeon, such as the physicians at Immigration Medical Exam Clinic, conducts the exam following USCIS and Centers for Disease Control and Prevention (CDC) guidelines.

Categories of Medical Conditions That Disqualify Immigration
The CDC and USCIS have outlined four broad categories that can disqualify an applicant on health grounds:
- Communicable Diseases of Public Health Significance
- Failure to Provide Required Vaccinations
- Physical or Mental Disorders with Harmful Behavior
- Substance Abuse or Addiction
Each of these categories includes specific conditions and requirements, which we explain below.
1. Communicable Diseases of Public Health Significance
One of the main reasons an applicant may be denied is if they test positive for a contagious disease that could spread in the community.
Tuberculosis (TB)
- Testing: Immigration applicants must undergo a TB screening, usually starting with an Interferon-Gamma Release Assay (IGRA) blood test.
- Chest X-Ray: If the test is positive, a chest x-ray is required to check for active TB.
- Disqualification: Active TB is a disqualifying condition until treatment is completed.
Syphilis
- Testing: A blood test is used to screen for syphilis.
- Disqualification: Active, untreated syphilis makes an applicant inadmissible until treatment is finished.
Gonorrhea
- Testing: A urine test is required.
- Disqualification: Untreated gonorrhea can disqualify applicants, but treatment usually resolves the issue.
Other Diseases
In the past, HIV was considered a disqualifying condition, but it is no longer listed as a ground of inadmissibility. The CDC updates the list of diseases based on public health needs, so applicants should stay informed before their exam.
2. Failure to Show Proof of Vaccinations
USCIS requires applicants to receive certain vaccines to protect both the applicant and the community.
Required Vaccinations May Include:
- Measles, Mumps, Rubella (MMR)
- Polio
- Tetanus and Diphtheria
- Pertussis
- Hepatitis B
- Varicella (chickenpox)
- Influenza (during flu season)
- COVID-19 vaccine
What Happens Without Proof?
If an applicant does not have documentation or refuses to receive required vaccinations, their immigration application may be denied. Civil surgeons at Immigration Medical Exam Clinic can provide missing vaccinations during the exam.
3. Physical or Mental Disorders with Associated Harmful Behavior
Some health conditions are not disqualifying on their own, but they become grounds for inadmissibility when linked with harmful behavior.
Examples of Harmful Behavior:
- Violence toward others
- Self-harm attempts
- Behavior that interferes with public safety
For instance, a mental health condition like depression does not disqualify someone automatically. However, if there is a recent history of dangerous behavior related to the condition, USCIS may consider the applicant inadmissible.
Civil surgeons carefully review medical history, treatment records, and behavior reports when completing Form I-693.
4. Substance Abuse or Addiction
Drug abuse or addiction is another condition that can disqualify immigration applicants.
Key Points:
- Current Use: Applicants who currently use controlled substances are considered inadmissible.
- History of Use: A past history may not automatically disqualify someone if they are in recovery and no longer dependent.
- Screening: The medical exam includes a review of medical history and questions about substance use.
Substance-related conditions are taken very seriously because they may affect both public health and safety.
Other Conditions That May Affect Immigration Approval
While the categories above are the main medical grounds of inadmissibility, there are other considerations applicants should be aware of.
Pregnancy and Immigration Exams
Pregnancy does not disqualify immigration. However, some tests like chest x-rays may be delayed or done with extra precautions.
Chronic Illnesses
Conditions such as diabetes, hypertension, or asthma do not disqualify applicants. The focus is mainly on contagious diseases and behaviors linked to safety risks.
Mental Health Conditions Without Harmful Behavior
Applicants with conditions like anxiety, depression, or bipolar disorder can still qualify, provided there is no associated harmful conduct.
Waivers of Inadmissibility
In some cases, applicants who are found inadmissible for medical reasons can apply for a waiver of inadmissibility.
- Communicable Disease Treatment: If an applicant completes treatment, they may reapply.
- Vaccination Waivers: Religious or moral exemptions may be available.
- Mental Health Conditions: If an applicant can show stability and treatment compliance, USCIS may reconsider.
Waivers are reviewed individually and require legal and medical documentation.
Preparing for the Immigration Medical Exam
Knowing what to expect during the medical exam helps applicants avoid unnecessary delays. At Immigration Medical Exam Clinic, the process typically includes:
- Medical History Review – Questions about past illnesses, mental health, and substance use.
- Physical Examination – General health check including vital signs.
- Laboratory Testing – TB blood test, syphilis blood test, and gonorrhea urine test.
- Vaccination Review – Verification of required vaccines, with updates provided if needed.
- Form I-693 Completion – Results are sealed in an envelope for submission to USCIS, with a copy for the applicant’s records.

How Applicants Can Improve Their Chances
- Bring Records: Provide vaccine history, prescriptions, and past medical records.
- Complete Treatment: If you have a condition like TB or syphilis, complete treatment before your exam.
- Be Honest: Answer questions truthfully—false information can result in denial.
- Choose the Right Clinic: A certified civil surgeon, such as those at Immigration Medical Exam Clinic, ensures the process follows USCIS requirements.
Trusted Immigration Doctor in Houston – Serving the Larchmont Community
When it comes to your immigration journey, every step matters including choosing the right clinic for your medical exam. At Immigration Medical Exam Clinic, we are proud to be the trusted immigration doctor Houston residents rely on, especially in the Larchmont area.
Why Choose Us?
✅ Experienced Civil Surgeons – Our doctors are certified to perform immigration medical exams required by USCIS. We handle every step with professionalism and care.
✅ Convenient for Larchmont Residents – Located near you, our clinic provides easy access for individuals and families in Larchmont who need reliable immigration medical services.
✅ Comprehensive Testing & Vaccinations – From TB (IGRA), syphilis, and gonorrhea testing to completing required vaccinations, we make sure everything is done according to USCIS and CDC guidelines.
✅ Fast & Accurate Results – We know how important timing is for immigration applications. That’s why we work efficiently to complete and seal your Form I-693 while providing you with a copy for your records.
✅ Compassionate Care – Immigration can feel overwhelming, but we’re here to make the process smoother with clear instructions, friendly support, and patient-centered care.
Choosing the right immigration doctor in Houston can make a big difference in your journey. If you’re in Larchmont and preparing for your medical exam, let Immigration Medical Exam Clinic be your trusted partner.
📞 Call us today to schedule your appointment and take the next step toward your immigration goals with confidence.
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Immigration Medical Exam Clinic is dedicated to serving the diverse needs of the local community of Houston, including individuals residing in neighborhoods like Larchmont With its convenient location near landmarks such as the Westpark/Lower Uptown Transit Center and major intersections like Terminal St. and N 1st St. (coordinates: 29.72569368908686, -95.46274200350685), we offer immigration doctor Houston services.
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Conclusion
The question “What conditions disqualify immigration?” is an important one for anyone starting the immigration process. While certain health conditions such as active tuberculosis, untreated syphilis, gonorrhea, lack of vaccinations, substance abuse, or mental health conditions tied to harmful behavior can cause disqualification, many applicants successfully complete the process by being prepared and addressing issues early.
At Immigration Medical Exam Clinic, we guide applicants through every step, from required tests to vaccination updates, ensuring compliance with USCIS and CDC rules. Understanding what to expect reduces stress and helps applicants move forward confidently in their immigration journey.
FAQs
1. What medical conditions can disqualify someone from immigration?
Certain conditions may make an applicant inadmissible, including active tuberculosis, untreated syphilis, untreated gonorrhea, failure to provide proof of required vaccinations, substance abuse, and physical or mental disorders linked to harmful behavior.
2. Do chronic illnesses like diabetes or high blood pressure affect immigration approval?
No. Conditions such as diabetes, hypertension, or asthma do not disqualify applicants. The immigration medical exam focuses mainly on communicable diseases and health conditions that pose a risk to public safety.
3. Can mental health conditions disqualify an applicant?
Mental health conditions by themselves do not disqualify someone. However, if the condition is connected to harmful behavior—such as violence or self-harm—it may be considered a ground for inadmissibility.
4. What vaccinations are required for the immigration medical exam?
USCIS requires vaccines such as MMR (measles, mumps, rubella), polio, tetanus-diphtheria, pertussis, hepatitis B, varicella, influenza (during flu season), and COVID-19. If applicants are missing any, the civil surgeon can provide them during the exam.
5. What happens if I test positive for tuberculosis or another disqualifying condition?
If an applicant tests positive for active TB or another communicable disease, they must complete treatment before they can be cleared. Once treatment is documented and confirmed, the applicant may continue with their immigration process.
